Includes official and accepted business languages spoken in this country/economy.Last Published:4/17/2016Panama's official language is Spanish. However, English is often spoken in major cities and tourist destinations.Prepared by our U.S. Embassies abroad. With its network of 108 offices across the United States and in more than 75 countries, the U.S. Commercial Service of the U.S. Department of Commerce utilizes its global presence and international marketing expertise to help U.S. companies sell their products and services worldwide. Locate the U.S. Commercial Service trade specialist in the U.S. nearest you by visiting http://export.gov/usoffices.